Literature Review and Case Report about Pediatric Anti-NMDAR Encephalitis

Rong Xiao

Published Date: 2020-06-19
Visit for more related articles at

Abstract

Objective: Literature review about pediatric anti-NMDAR encephalitis after reporting four patients hospitalized at a tertiary children’s hospital.
Methods: Four patients (age 9, 16, 4, 2) with neuropsychiatric symptoms at a tertiary children ’ s hospital between Jan 1, 2011 to Dec 31, 2016 were identified though a query of hospital billing data. Diagnosis was confirmed by the detection of IgG anti-GluN1 antibodies in either serum or in Cerebrospinal Fluid (CSF).
Results: Neuropsychiatric symptoms are very common,often interfering with care. Psychiatry were consulted in 3 cases.
Conclusions: Antipsychotics are commonly used to treat aggression, psychosis and delirium. Benzodiazepines could be helpful for catatonia and aggression but could worsen delirium. Clonidine could be helpful for agitation,insomnia, and/or autonomic instability. Electroconvulsive Therapy (ECT) could be helpful for malignant catatonia.

open access journals, open access scientific research publisher, open access publisher
Select your language of interest to view the total content in your interested language

Viewing options

Flyer image

Share This Article